di-Potassium hydrogen phosphate trihydrate or Dipotassium hydrogen phosphate trihydrate or Potassium phosphate dibasic trihydrate or Dipotassium hydrogen orthophosphate trihydrate
Product Overview & Quality
- Product Name: di-Potassium hydrogen phosphate trihydrate or Dipotassium hydrogen phosphate trihydrate or Potassium phosphate dibasic trihydrate or Dipotassium hydrogen orthophosphate trihydrate
- Brand: QReC (Product Code: QR-D3211-1-0500)
- Grade: Analytical Reagent (AR Grade) featuring a certified chemical purity of not less than 99.0 percent. Manufactured and multi-crystallized under strict QReC global laboratory specifications, maintaining stoichiometric trihydrate hydration. Rigorously tested to enforce ultra-low ppm thresholds of water-insoluble matter, chloride, sulfate, total nitrogen, silica, and trace heavy metals (such as iron, lead, copper, arsenic, zinc, sodium, calcium, and magnesium). Conforms to certified DNase and RNase-free specifications, ensuring biological inertness in molecular biology and biochemical workflows. Exhibits excellent crystal uniformity with minimal background ultraviolet absorbance, dissolving cleanly and rapidly in water to produce transparent, residue-free buffer solutions. Packaged in a heavy-duty, moisture-barrier polymer container equipped with a hermetic seal.
- Physical Properties: Colorless crystals or white crystalline powder. Odorless. Thermodynamically stable under ambient conditions with slight hygroscopicity in high humidity. Aqueous solutions are mildly alkaline (pH approximately 8.7 to 9.3 for a 5 percent aqueous solution at room temperature). Non-combustible and non-corrosive solid.
- Solubility: Freely and highly soluble in water (approximately 160 to 170 grams per 100 milliliters at 20 degrees Celsius; dissolves noticeably faster and with higher solubility than corresponding sodium phosphate salts, increasing further in warm water); slightly soluble in ethanol; insoluble in diethyl ether.
- Key Use: Heavily utilized as the primary alkaline component paired with potassium dihydrogen phosphate (monopotassium phosphate) to prepare physiological Potassium Phosphate Buffer formulations (pH 5.8 to 8.0) for cell culture, enzyme kinetics, protein chemistry, and molecular biology. Extensively applied as an essential nutritional source of both bioavailable potassium and phosphorus in microbiological culture media (bacteria, yeast, and fungal broths) and fermentation processes, functioning concurrently as an internal pH buffer. Universally employed as an inorganic buffer modifier in High-Performance Liquid Chromatography (HPLC) mobile phases to regulate analyte ionization and enhance chromatographic peak symmetry. Widely used in protein purification workflows, salting-out fractionation, and diagnostic reagent compounding.
Safety & Hazards
- Classification: Non-hazardous substance under standard GHS criteria in typical laboratory usage. Exceptionally low acute toxicity profile; particulate dust may exert mild mechanical irritation to ocular, dermal, and respiratory surfaces.
- Health Risks: Direct eye contact may cause transient mechanical stinging, conjunctival redness, or lacrimation. Prolonged dermal contact may produce mild dryness or superficial irritation. Inhalation of particulate dust can cause minor sneezing, coughing, or upper respiratory tickling. Ingestion of excessive quantities may provoke transient gastrointestinal upset, abdominal cramps, or osmotic diarrhea due to potassium and phosphate salt concentration.
- First Aid Measures: Flush affected eyes thoroughly with clean running water for at least 10 to 15 minutes. Wash exposed skin with soap and water. In case of dust inhalation, relocate the individual to fresh air. If accidentally swallowed in substantial amounts, rinse mouth thoroughly, drink water, and seek medical advice if discomfort persists.
Handling & Storage
- Storage: Stable Hydrated Buffer Salt. Must be preserved in its original, tightly closed QReC container. Store in a clean, strictly dry, cool, and well-ventilated dedicated chemical store at stable room temperature (below 25 to 30 degrees Celsius), sheltered from atmospheric moisture and direct solar radiation. Keep strictly segregated from strong mineral acids (which induce exothermic neutralization reactions) and strong oxidizing agents.
- Precautions: Standard laboratory PPE is mandatory, including protective gloves, safety glasses, and a protective lab coat. Re-seal container cap tightly immediately after sampling. Minimize dust generation during weighing and dispensing.









