Sodium ethanoate trihydrate or Acetic acid sodium salt trihydrate

Product Overview & Quality

Product Name: Sodium acetate trihydrate 99.5% or Sodium ethanoate trihydrate or Acetic acid sodium salt trihydrate
Brand: QReC (Product Code: QR-S5022-1-0500
Grade: Analytical Reagent High Purity Grade (AR Grade) featuring an exceptional certified chemical assay of not less than 99.5 percent in a 500 g laboratory container. Manufactured and multi-recrystallized under strict QReC global laboratory specifications without anti-caking conditioning additives, strictly maintaining stoichiometric trihydrate crystalline hydration. Rigorously tested to enforce minimal water-insoluble matter (strictly below 0.005 percent), along with ultra-low ppm limits of chloride, sulfate, phosphate, ammonium, calcium, magnesium, potassium, and trace heavy metals (such as iron, lead, copper, arsenic, and zinc). Conforms to certified DNase, RNase, and Protease-free specifications, ensuring biological purity in nucleic acid and molecular workflows. Displays exceptionally low background ultraviolet absorbance at 260 and 280 nanometers, dissolving completely and rapidly in water to yield crystal-clear, neutral-to-basic, particulate-free solutions. Packaged in a heavy-duty, moisture-barrier polymer container equipped with an airtight hermetic seal.
Physical Properties: Colorless translucent crystals, crystalline granules, or fine white crystalline powder. Odorless to faint acetic odor upon opening. Slightly efflorescent in dry ambient air, gradually losing water of crystallization. Melting point is approximately 58 degrees Celsius (readily liquefying in its own water of crystallization upon moderate heating). Non-combustible and non-corrosive solid. Aqueous solutions are mildly basic (pH approximately 7.5 to 9.2 for a 5 percent aqueous solution at room temperature).
Solubility: Readily and highly soluble in water (approximately 76 to 80 grams per 100 milliliters at 20 degrees Celsius, increasing to over 150 grams per 100 milliliters in boiling water); moderately soluble in ethanol (approximately 5 grams per 100 milliliters); practically insoluble in diethyl ether.
Key Use: Universally utilized as the standard reagent for routine nucleic acid precipitation (Ethanol/Isopropanol DNA and RNA precipitation) typically formulated as a 3 M stock solution (pH 5.2) in molecular biology, effectively neutralizing the negatively charged polyphosphate backbone to induce efficient condensation and precipitation. Extensively applied as the primary basic buffer component paired with acetic acid to prepare Sodium Acetate Buffer systems (pH 3.6 to 5.6) for enzymatic assays, restriction digests, protein crystallization, and gel electrophoresis. Heavily employed as an organic mobile phase buffer modifier in High-Performance Liquid Chromatography (HPLC) to optimize retention, peak symmetry, and ionization of basic pharmaceuticals and polar metabolites. Widely used as a stabilizing buffer in histological tissue staining and fixative formulations. Serves as an analytical reference standard and reagent in clinical diagnostics, food analysis, and general analytical chemistry.

Safety & Hazards

Classification: Non-hazardous substance under standard GHS criteria in routine laboratory usage. Exceptionally low acute toxicity profile; particulate dust may exert mild mechanical irritation to ocular, dermal, and respiratory surfaces.
Health Risks: Direct eye contact may cause transient mechanical stinging, conjunctival redness, or lacrimation. Prolonged dermal contact may produce mild dryness or superficial irritation. Inhalation of particulate dust can cause minor sneezing, coughing, or upper respiratory discomfort. Ingestion of excessive quantities may provoke transient gastrointestinal upset, abdominal cramps, nausea, or osmotic laxative effects characteristic of concentrated sodium and acetate salts.
First Aid Measures: Flush affected eyes thoroughly with clean running water for at least 10 to 15 minutes. Wash exposed skin with soap and water. In case of dust inhalation, relocate the individual to fresh air. If accidentally swallowed in substantial amounts, rinse mouth thoroughly, drink water, and seek medical advice if discomfort persists.

Handling & Storage

Storage: Stable Analytical Organic Salt. Must be preserved in its original, tightly closed QReC container. Store in a clean, strictly dry, cool, and well-ventilated dedicated chemical store at controlled temperatures (below 25 to 30 degrees Celsius), sheltered from atmospheric moisture and direct sunlight. Keep strictly segregated from strong oxidizing agents and concentrated mineral acids (contact with strong mineral acids liberates pungent acetic acid fumes).
Precautions: Standard laboratory PPE is mandatory, including protective gloves, safety glasses, and a protective lab coat. Re-seal container cap tightly immediately after sampling to prevent efflorescent dehydration or moisture uptake. Minimize dust generation during weighing and dispensing.