Sodium dihydrogen phosphate monohydrate

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Sodium dihydrogen phosphate monohydrate

Sodium dihydrogen phosphate monohydrate or Monosodium phosphate (MSP) or Sodium biphosphate or Sodium acid phosphate

Product Overview & Quality

  • Product Name: Sodium dihydrogen phosphate monohydrate or Monosodium phosphate (MSP) or Sodium biphosphate or Sodium acid phosphate
  • Brand: QReC (Product Code: QR-S5108-1-1000)
  • Grade: Analytical Reagent (AR Grade) featuring a high certified chemical assay of not less than 98 to 99 percent. Manufactured and multi-crystallized under strict QReC global laboratory specifications. Rigorously analyzed to maintain ultra-low ppm thresholds of chloride, sulfate, total nitrogen, water-insoluble matter, and trace heavy metals (such as iron, lead, copper, and arsenic). Conforms to certified DNase, RNase, and Protease-free specifications, ensuring non-destructive physiological conditions in life science workflows. Dry, uniform crystals dissolve cleanly and rapidly in water, yielding transparent, residue-free buffer solutions. Packaged in a heavy-duty, moisture-barrier polyethylene container with a tight hermetic seal.
  • Physical Properties: Colorless crystals or white crystalline powder. Odorless. Slightly hygroscopic. Aqueous solutions are mildly acidic (pH approximately 4.1 to 4.5 for a 5 percent aqueous solution at ambient temperature). Non-flammable and non-corrosive.
  • Solubility: Freely and highly soluble in water (approximately 85 grams per 100 milliliters at room temperature; solubility increases in hot water); practically insoluble in ethanol, diethyl ether, and chloroform.
  • Key Use: Heavily utilized as the foundational acidic component paired with disodium hydrogen phosphate to formulate standard Phosphate Buffer (PB) and Phosphate-Buffered Saline (PBS) systems, maintaining physiological pH conditions (pH 5.8 to 8.0) in cell culture, molecular biology, biochemistry, and immunodiagnostic assays. Extensively applied as an inorganic buffer salt modifier in High-Performance Liquid Chromatography (HPLC) mobile phases to stabilize solute ionization states and improve chromatographic peak symmetry. Routinely employed in enzymatic kinetics and protein purification procedures. Serves as a primary reference standard for inorganic phosphate determinations in chemical and clinical analytical laboratories.

Safety & Hazards

  • Classification: Non-hazardous substance under standard GHS criteria in typical laboratory quantities. Low acute toxicity profile; particulate dust may exert mild mechanical irritation to eyes, skin, and mucosal membranes.
  • Health Risks: Direct eye contact may cause transient mechanical irritation, redness, and lacrimation. Prolonged dermal contact may produce mild dryness or superficial skin irritation. Inhalation of particulate dust may induce sneezing, coughing, or minor upper respiratory discomfort. Ingestion of excessive quantities may provoke transient gastrointestinal upset, osmotic diarrhea, or abdominal cramps due to phosphate salt accumulation.
  • First Aid Measures: Flush affected eyes thoroughly with clean running water for at least 10 to 15 minutes. Wash exposed skin with soap and water. In case of dust inhalation, transfer the individual to fresh air. If accidentally ingested in significant amounts, rinse mouth with water, drink water, and seek medical advice if discomfort persists.

Handling & Storage

  • Storage: Slightly Hygroscopic Inorganic Salt. May cake or form clumps if exposed to ambient humidity. Must be preserved in its original, tightly closed QReC plastic container. Store in a clean, dry, cool, and well-ventilated chemical store at stable room temperature (below 25 to 30 degrees Celsius), sheltered from humidity and direct sunlight. Keep strictly segregated from strong alkalis, strong oxidizing agents, and excessive moisture.
  • Precautions: Standard laboratory PPE is mandatory, including chemical-resistant gloves, safety glasses, and a protective lab coat. Minimize dust generation during weighing and dispensing. Re-seal container cap tightly immediately after sampling to preserve crystal integrity.
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