Tris (Hydroxymethyl) aminomethane (Tris Base / THAM)
Product Overview & Quality
- Product Name: Tris (Hydroxymethyl) aminomethane (Tris Base / THAM)
- Grade: Analytical Reagent (AR Grade), providing high purity and minimal trace metals for sensitive biochemical and molecular applications.
- Physical Properties: Odorless, white crystalline powder.
- Solubility: Highly soluble in water; aqueous solutions are slightly alkaline.
- Key Use: A primary biological buffer used to maintain stable pH (effective range: pH 7.0 – 9.0). Essential for DNA/RNA electrophoresis (TAE, TBE buffers) and protein analysis (SDS-PAGE).
Safety & Hazards
- Classification: Categorized as an irritant to the skin, eyes, and respiratory system.
- Health Risks: Direct contact may cause redness and irritation of the eyes and skin. Inhalation of dust may irritate mucous membranes.
- First Aid Measures: Flush affected eyes or skin with plenty of water. Move to fresh air if dust is inhaled. If swallowed, rinse mouth thoroughly and seek medical advice.
Handling & Storage
- Storage: Store in a cool, dry place in a tightly sealed container. The substance is hygroscopic and can absorb carbon dioxide from the air, which may affect its buffering capacity.
- Precautions: Wear standard PPE, including chemical-resistant gloves and safety goggles. Avoid dust generation. Store away from strong oxidizing agents and strong acids.







